Anti-TNF-α therapy modulates resistin in patients with rheumatoid arthritis
نویسندگان
چکیده
Objective Chronic systemic infl ammation plays a pivotal role in the development of atherosclerosis in rheumatoid arthritis (RA). In the present study, we investigated whether anti-TNF-α antagonist-monoclonal antibody-infl iximab administration alters circulating levels of resistin, a proinfl ammatory adipokine. We further assessed associations of circulating resistin concentrations with CRP and ESR levels, platelet counts and metabolic syndrome and demographic characteristics in RA patients on periodical treatment with infl iximab.
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